Each box includes 5 units
Isolating the beneficial signals given out by stem cells and using them rather than the stem cells themselves are the next generation as a therapy. This makes sense, as other cells react to these signals and change their behavior accordingly. There is a tremendous therapeutic potential of extracellular vesicles, particularly exosomes.
100% Natural. No animal products. GMO Free.
Purified Cord Blood MSC Exosomes in saline.
Cellgenic Exosomes is a purified xeno-free, chemically defined, cell-free cord blood MSC derived exosome re-suspended in 0.9% normal saline. Contains over 30 billions purified MSC exosomes per vial.
PRODUCT DESCRIPTION:
Since few transplanted cells persist in vivo, the beneficial effects of cell therapy may lie in the secreted factors being the active component of this treatment.
A key part of paracrine secretion is Exosomes, which are membrane vesicles that are stored intracellularly in endosomal compartments and are secreted when these structures fuse with the cell plasma membrane.
- Exosomes contain protein, DNA, and RNA, thus making them an attractive vector of paracrine signals delivered by stem cells.
- Exosomes may also be “loaded” with predetermined proteins and nucleic acid to achieve a desired effect (1).
- Exosomes can be stored as an “off-the-shelf” product having the potential for circumventing many of the limitations of\viable cells for therapeutic applications in regenerative medicine.
- In vitro, exosomes from pre-adipocytes stimulate cell proliferation in a wound healing model.
- In vivo, adipose-graft derived exosomes have been shown to be a promising tool for skin repair and remodeling (2)
COMPONENTS OF CELLGENIC EXOSOMES
Exosomes, Cytokines, Chemokines, Growth Factors, Hyaluronic Acid (HA)
EXOSOMES CAN DELIVER THESE SIGNALS
Anti-Apoptotic, Anti-Fibrotic, Pro-Angiogenic, Pro-Differentiation, Pro-Proliferation, Immunomodulatory, Immune Privileged
