Cellgenic Amniotic Fluid-Human placental Derived


CELLGENIC AF is a connective tissue allograft flowable matrix. It’s derived from chorion-free human placental tissue and amniotic fluid, cryopreserved to maintain the viability of the intercellular messengers. CELLGENICTM retains the biologic functionality that ensures symmetrical structure development, growth, and repair of the soft tissue by acting as a biologic matrix for use in filling defects, or for points of localized inflammation.



  • The placental Extracellular Matrix (ECM) modulates correct cellular reconstruction rather than scar tissue formation. This ECM includes growth factors, fibronectin, laminin, hyaluronic acid, proteoglycans, and other proteins. Anti-inflammatory and anti-fibrotic proteins in placental ECMs reduce inflammation, fibrous tissue growth, and potential scar tissue formation as they downregulate TGF-B, suppress pro-inflammatory cytokines, and inhibit MMPs and fibroblast formation.
  • Placental ECMs contain Collagens I, III, IV, V, VI, VII, and fibrous proteins that provide a structural scaffold to support migration. Fibronectin, integrins, laminin, and hyaluronan also play a key role in proliferation, differentiation and adherence to the scaffold.

Additional information


0.5 ml, 1.0 ml, 2.0 ml


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